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The increased Bax/Bcl-2 ratio promotes mitochondrial outer membrane permeabilization and cytochrome c release, leading to the activation of caspase-9 and downstream executioner caspase-3 (78)

Moreover, selective c-Met inhibitors are superior to non-selective c-Met inhibitors in the treatment of liver cancer due to their low toxicity

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Because the nuclear localization of -catenin is crucial in cellular processes such as proliferation, division, and differentiation 4 , confocal microscopy was utilized to study the subcellular localization of -catenin in hDP cells treated with NTAPP at various output voltages