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Previous research by the same team has shown that pneumococcal bacteria use PAFR to help them stick to airway cells, which in turn increases the ability of bacteria to invade body tissues and cause disease

CCSP is predominantly expressed in club cells, a non-ciliated secretory epithelial cell subtype that is ubiquitously expressed in murine lungs (57, 58), although some studies indicate a possible subset of cells where CCSP is expressed during development (49) or in models of infection (50)