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This article looked at young adults (aged 18-24 years) who were current or former e-cigarettes users and had no respiratory disease or symptoms prior to entering the study

Ganapathy V, Manyanga J, Brame L, McGuire D, Sadhasivam B, Floyd E, Rubenstein DA, Ramachandran I, Wagener T, Queimado L (2017) Electronic cigarette aerosols suppress cellular antioxidant defenses and induce significant oxidative DNA damage

Smoking damages the lungs at every puff, filling them with tar and harmful chemicals that limit oxygen flow

So if the wire(s) are run from your fuse panel from a fused circuit you do not need to fuse them again