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WITHOUT BUTANE

Absolute or relative contraindication to bupropion use are pregnancy and breastfeeding, history of seizures, epilepsy, brain and cranium neoplasms, current or prior diagnosis of bulimia or anorexia nervosa, simultaneous discontinuation of alcohol or sedatives/benzodiazepines, current use of monoaminoxydase inhibitors or use of these drugs in the previous 14 days [12]

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The FDA also wants to know what the unintended consequences of lowering levels of nicotine could be, such as people inhaling deeper or smoking more cigarettes to compensate for the difference