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In 2002, a smoke-free restaurant ordinance was implemented and, in 2007, all workplaces, including bars, became smoke free

As early as 1928, statistical data began to appear and showed a higher proportion of heavy smokers among lung cancer patients [4]

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We therefore adjusted for this by multiplying the F AA by the frequency of alcohol-consumers who are never-smokers (53%), and the F TA by the frequency of smokers who do not consume alcohol (12%), for cancers in which both alcohol and tobacco are known risk factors (Additional file 1: Table S2)