Moreover, Flaskerud raising a question When did we lose our right to be lazy, unhealthy, and politically incorrect? [32]
Wells were the favourite authors of my boyhood) in the sunlit, sleeping dormitory
However, there is currently little evidence for this association in humans, and rs16969968/rs1051730 has not been identified in genome-wide association studies of depression or anxiety to date.49 ,58 ,59 It is important to note that stratifying by the measured exposure variable in Mendelian randomisation studies can lead to collider bias.60 ,61 In this specific analysis, if both the genetic variant and anxiety cause individuals to smoke, then stratifying on smoking could, in theory, induce an association between the variant and anxiety.13 We do not think that collider bias is likely to be a major issue in these analyses because rs16969968/rs1051730 does not appear to be associated with smoking initiation in this sample (see online supplementary figure S9) or in previous studies.29 ,30 There is, however, as reported previously in a few specific populations36 ,62 ,63 some evidence that the minor allele of rs16969968/rs1051730 is associated with smoking cessation
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