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I was surprised that results were still significant when we compared the nonage-matched groups because that includes younger patients who presumably have had less lifetime exposure to smoke, he said

it was faintly shamanistic , really

Exceptions to this, such as North Shore, which was cytotoxic (51% of control) but did not have a cytotoxic level of flavor chemicals, suggest that our target list of chemicals does not contain some of the flavor chemicals that are used in refill fluids, that chemicals act additively or synergistically to produce cytotoxicity, or that another factor, such as a metals 19 , caused cytotoxicity in this product

(International Organization for Standardization, 2012)