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these signs can be reversible following giving up smoking for good

However, epidemiological studies assessing Swedish smokeless tobacco, which exposes users to nicotine without combustion products, generally have not found an increased risk of myocardial infarction or stroke among users, but suggest that nicotine might contribute to acute cardiovascular events, especially in those with underlying coronary heart disease

While the analyses adjusted for the use of other tobacco products including cigars, cigarillos, and other combustible tobacco, the adjustment was done based on current use, and did not distinguish between former and ever use of other combustible tobacco products

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