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While the current but still limited literature suggests that e-cigarette use may lead to fewer negative cardiovascular effects than conventional cigarettes, our review supports that there is not sufficient data to conclusively make these resolutions. They urge that e-cigarettes be subject to the kind of pre-market scientific reviews that are required of other drugs

Peer review Peer review information Communications Biology thanks Yesim Bilmez, Savni Sawant, and the other, anonymous, reviewer for their contribution to the peer review of this work

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To find the equivalence: 20mg/ml of nicotine from the pod 1 to 2 milligrams absorbed per cigarette = 20 to 40 cigarettes