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Two systematic reviews of the literature (reviewing 54 studies that show the impact of plain tobacco packaging) have found that plain packaging as opposed to branded packs (1) reduces package appeal, (2) increases visibility and salience of health warnings, and (3) reduces confusion about the harm associated with use that has been shown to result from packs with corporate branding [28, 29]

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Thus, to further explore whether the protection of airway epithelial barrier is the common pharmacological activity of macrolides, we have repeated the in vitro experiments using erythromycin (EI, 14-membered ring macrolide) and spiramycin (SPI, 16-membered ring macrolide)

It is most common in older adults and women