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Future research should prioritize prospective cohort studies with comprehensive exposure metrics and meticulous control for confounding variables, including occupational and environmental factors

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Oxidative Stress and Inflammation Chemicals from smoking trigger the release of free radicals

To assess if the association between smoking and drinking differs by city, the Bayesian information criterion (BIC) test was conducted for two models: a full model included drinking, city, and the interaction effect of the drinking and city as independent variables, controlling for age, gender, race/ethnicity, education