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In animal models, mice were exposed for 60 weeks to the e-cigarette with a concentration of nicotine from 0 to 24 mg/mL showed endothelial dysfunction and an increase in endothelial ROS, in addition to a thickening of the vessel wall were dependent on nicotine concentration (186)

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had marijuana use disorder in 2019, according to the 2019 National Survey on Drug Use and Health

Associated with this phenotype, we also found increased levels of serum FFA and oxidative stress (39)