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When tested in the lungs, DNA methylation correlated inversely with the levels of AHRR mRNA in both smokers and non-smokers ( AHRR encodes a transcription factor that inhibits the aryl hydrocarbon receptor pathway, which enhances the expression of detoxification (xenobiotic-metabolizing) enzymes of environmental pollutants, such as polycyclic aromatic hydrocarbons contained in cigarette smoke (Opitz et al., 2011)

Since its founding in 2009, Uber has acquired numerous other businesses that have helped make itself into one of the most valuable startups today

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