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The presence of nicotine also suppresses inflammatory factors such as MUC5AC in airway epithelial cells [95]

Summary What is known about this topic Cigarette smoking is a well-established cardiovascular risk factor, but population-based evidence on the association between e-cigarette use and hypertension remains inconsistent, particularly when exclusive e-cigarette use, dual use, and smoking history are not clearly distinguished

An estimated 93,000 deaths each year in Italy are attributed to smoking, according to the health ministry

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