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The study The aim of this study was to determine the relationship between smoking (including the usage of HNB tobacco) and alcohol intake with immunoglobulin (Ig)G antibody titers against SARS-CoV-2 spike protein in personnel of Japanese national medical research facilities who received two doses of BNT162b2 vaccination

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Methadone was assessed as less harmful than standard opioid analgesics, which viewpoint might be biased by addiction medicine physicians' conception of methadone primarily as a standard opioid dependence maintenance treatment, which in this context has been repeatedly shown to reduce morbidity and mortality ( It cannot be excluded that our ratings may be biased toward metropolitan rather than rural perception of substance use harms