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Although Lorazepam injection is indicated only for intermittent use (see INDICATIONS AND USAGE and DOSAGE AND ADMINISTRATION), if used more frequently than recommended, abrupt discontinuation or rapid dosage reduction of Lorazepam injection, or administration of flumazenil (a benzodiazepine antagonist) may precipitate acute withdrawal reactions, which can be life-threatening (e.g., seizures) (see DRUG ABUSE AND DEPENDENCE, Dependence)

They can also exacerbate other symptoms particularly psychological ones

As time has progressed there has been a change and shift in the confidence of the younger women at Nonnatus House

Wigand told 60 Minutes that when he went to a meeting with Sandefur, Sandefur told him that removing it would impact sales