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Screening is recommended at a younger age (and more often) for those who have risk factors for colon cancer, such as: A strong family history of colorectal cancer or certain types of polyps A family history of a hereditary colorectal cancer syndrome such as familial adenomatous polyposis or Lynch syndrome A personal history of colorectal cancer or certain types of polyps A personal history of inflammatory bowel disease (IBS), such as Crohn's disease or ulcerative colitis A personal history of radiation to the abdomen or pelvis to treat cancer Besides undergoing a colonoscopy every 10 years (or earlier, depending on a person's prior test results and risk profile), there are other colon cancer screening options, including: An annual fecal occult blood test (guaiac test) An annual fecal immunochemical test (FIT test) A stool DNA test every three years A blood test every three years Virtual colonoscopy every five years Flexible sigmoidoscopy every five to 10 years Your healthcare provider may recommend one over another depending on several factors