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However, modern tobacco packaging increasingly incorporates multi-layer constructions combining paperboard with aluminum foil liners, plastic vapor barriers, or specialized coatings that enhance moisture resistance and aroma retention

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10.1212/01.WNL.0000150901.47293.BC Acknowledgements The authors would like to thank Sara Balduzzi of the Italian Cochrane Centre for her valuable help and for critically reading the manuscript

The smoke from cannabis contains a similar array of harmful chemicals to that of tobacco smoke, including carcinogens and substances that can irritate the bronchial passages