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Subsequently, various chemokines and growth factors refined by activated endothelial cells and macrophages act on adjacent smooth muscle cells (or their precursor 12), inducing their proliferation and synthesis of extracellular matrix components in the intimal compartment, resulting in fibromuscular plaques [104]

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When the rate hike was announced, Washington estimated that the sale of tax-paid cigarettes would drop by about 10 percent, or 1.7 billion packs, in the following year

As Table 5-2 shows, removing the effects of smoking-related mortality increases Japanese life expectancy in both men (by 2.05 years) and women (0.75 year) by values that are close to the average for the rest of the countries in the study