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That said, it is important to bear in mind that heat-not-burn tobacco sticks are not the same as cigarettes but have been designed specifically for use with heated tobacco vapes
The cumulative exposure to smoking, often quantified in pack-years, significantly impacts risk, but non-smoking factors are increasingly recognized, especially in low- and middle-income countries
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The differences in smoking patterns, including the number of puffs, the puff volume, and whether the smoker blocks the ventilation holes greatly influence the delivery of smoke constituents to the smoker
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