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The Cigarette Renaissance Data published by the Centers for Disease Control and Prevention in 2024 found that nearly one in 20 adults in the United States aged 18 to 24 used cigarettes in 2022, although the figure was almost three times higher for those aged 25 to 44

Cotinine has a half-life of about 16 hours, according to the Centers for Disease Control and Prevention (CDC)

In addition to e-cigarettes, there is one more popular substitute for conventional cigarettes, namely heated tobacco products or heat-not-burn products