cigarette smoke mtros lung epithelial cells Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium Oxidative stress and inflammation: elucidating

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Novel pulmonary imaging of lung structure and function in symptomatic and asymptomatic e-cigarette smokers Nominated Principal Investigator Grace Parraga University of Western Ontario [email protected] [email protected] Principal Investigator Constance A Mackenzie Knowledge User Constance Mackenzie University of Western Ontario Co-investigators Karen J Bosma Inderdeep Dhaliwal Alexei Ouriadov Project Summary Modern electronic (e)-cigarettes were commercially developed in 2003 in China to provide an inhalable nicotine delivery device for current cigarette smokers in a safer, non-combustible manner with the long-term goal being harm reduction and enhanced combustible cigarette smoking cessation rates