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a Turkish population survey and a German population-based study, found correlation between smoking and multinodular goiter in both sexes.[] The association seems to be specific for thyroid multinodularity as smoking has not been associated with solitary thyroid nodules.[] In contrast, almost an equal number of studies[] report no relation of goiter frequency with smoking habits

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If dependence is present, what is the product type (cigarettes, chewing tobacco, other) and are there any associated complications or withdrawal symptoms? Tobacco dependence (F17.21x) carries significant risk-adjustment and quality measure implications that tobacco use (Z72.0) does not