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To further test the results estimated marginal means (EMMs) were computed using the emmeans package as post-hoc tests and p-values were corrected for multiple comparisons using Bonferroni-Holms method

Notably, IL-31RA expression is regulated by STAT3 within sensory neurons and remains elevated even after clinical resolution of inflammation, suggesting a pruritic memory mechanism that enables sustained neuronal activation independent of primary inflammatory cues (40)

The term Pop It Fresh refers to the capsule technology embedded in the cigarette filter

Knowing the risks of cigarette tar is key for those trying to detox from smoking