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Companies are promoting their products through television and radio advertisements that use celebrities, sexual content, and claims of independence to glamorize these addictive products and make them appealing to young people, said Centers for Disease Control and Prevention director, Thomas Frieden, in the reports foreword

This can be attributed to various risk factors, including genetic predispositions and mutations in genes like TP53 , HER2 , EGFR , KRAS , PIK3CA , and ALK