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We hypothesize that (1) participants who mainly use e-cigarettes work harder for e-cigarettes and show increased activation in the ventral striatum in the anticipation phase for e-cigarettes compared to tobacco cigarettes

In recent years, several companies have attempted to develop the drug as a prescription medication and an over-the-counter treatment

Finally, congeners may stimulate the body to release stress hormones, such as norepinephrine and epinephrine, causing an inflammatory response and worsening symptoms

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