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Oral submucous fibrosis Pathophysiology Habitual use of paan with areca nut (paan) triggers fibroblast proliferation and collagen synthesis, causing fibrosis of oral mucosa

Identifying and Managing Adverse Reactions Adverse reactions can vary but often include severe anxiety, paranoia, nausea, vomiting, and extreme sedation

Only one of the pairwise comparisons within smoking status/intensity category reached statistical significance: the aRR for adults currently smoking 1019 cigarettes per day (medium intensity) was significantly higher for those who started smoking before the age of 15 as compared to 15+ years ( p =0.027)

Take a shower Taking a shower might not immediately sober you up, but there's nothing like cold water to shock you back to reality