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[20] Randomized controlled trials have provided "high-certainty" evidence that e-cigarettes containing nicotine are more effective than nicotine replacement therapy for discontinuing tobacco smoking, and moderatecertainty evidence that they are more effective than e-cigarettes free of nicotine

COPD can involve several different kinds of lung diseases, including: Asthma, or the narrowing and swelling of the airways Emphysema, where the air sacs in the lungs lose their shape Chronic bronchitis, where the lining of the airways becomes inflamed and irritated Those who smoke may suffer from one or multiple lung diseases