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Lower moisture enables predictable, rapid combustion and prevents manufacturing problems during high-speed cigarette production (modern machines produce thousands of cigarettes per minute)

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We speculate, that modulating homeostatic balance in microglia, could have promising therapeutic potential in withdrawal, tolerance, and abstinence-related neural adaptations in nicotine addiction, in the adolescent brain

For instance, instead of documenting current tobacco user (Z72.0) clinicians might document currently smokes a few cigarettes a week when out with friends. This will not improve code selection, but it may help clinicians and investigators when looking for clues to tobacco-associated illness