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The cumulative impact of net inbound smuggling over the historical period, $83.8 billion, is much greater than the cumulative impact of net outbound smuggling, at only $4.31 billion

We must continue to work collectively to ensure youth are aware of these harms and fight back against Big Tobaccos nasty tricks to market their harmful products to children and youth

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Methods Materials and reagents The antibodies used in this study were obtained from the following sources: Rabbit anti-ZO-1 (#8193), rabbit anti-claudin-3 (#341700), rabbit anti-VE-cadherin (#D87F2), rabbit anti-VCAM-1 (#12367), mouse PECAM-1 (#89C2) from Cell Signaling Technology (Danvers, MA, USA)