A refillable pod can be a sensible next step for adults who want more flavor choice and a reusable device, but it does require charging, keeping e-liquid on hand, and replacing pods or coils when performance drops
The lungs and airways need to get used to the vapor, which has a different density and temperature compared to cigarette smoke
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At the time of manuscript submission, the trial was still in the recruitment phase, with 243 participants recruited as of 1st April 2019
