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VLNC cigarettes plus NRT (nicotine patch, gum and/or lozenge) significantly increased quit rates at all measured time points (3 & 6 weeks and 3 & 6 months) over use of NRT only VLNC found to be slightly better than nicotine replacement alone "Unlike the 0.3 mg cigarettes, 0.05 mg cigarettes were not associated with compensatory smoking behaviors

Some compounds become more bioavailable when heated, while others break down into entirely different molecules

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