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This process involves the inhalation of e-cigarette aerosols, which contain reactive oxygen species (ROS) and aldehydes that induce oxidative stress and inflammatory cytokine production, even in the absence of nicotine

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E-cigarettes may be safer than regular cigarettes for adults who are transitioning from smoking to vaping, but for youth who have never used any other tobacco products, nicotine experimentation could become nicotine addiction. The study was supported by the National Institutes of Health National Cancer Institute and the Food and Drug Administration Center for Tobacco Products (P50CA180905).