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It uses 100% natural whole-leaf tobacco without chemical additives

Funding This work was supported by the National Natural Science Foundation of China (81901006, 82372905), the Young Top-notch Talent of Pearl River Talent Plan (0920220228), the Guangdong Provincial Science and Technology Project Foundation (2022A0505050038), Science and Technology Program of Guangzhou (No.2025A04J3464), and Science Research Cultivation Program of Stomatological Hospital, Southern Medical University (PY2020002, PY2022019)

Vaping allows for more precise control over nicotine intake compared to smoking, potentially enabling gradual reduction

Tasks that require attention may feel more difficult when standing for prolonged periods