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In a CS-exposed mouse model (5 days/week for 46 months), genes associated with the TCA cycle, fatty acid oxidation, and redox regulation were compensatorily upregulated in pulmonary epithelial cells, accompanied by mitochondrial morphological and functional abnormalities including reduced cristae number, enlarged volume, decreased membrane potential, and reduced OCR

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In return, some of these groups have helped the industry fight anti-smoking measures

Juul, the Silicon Valley startup thats taken over three-quarters of the US e-cigarette market, has repeatedly declared it is in the business of helping adult smokers quit tobacco