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29 Xie et al suggested that long-term tobacco smoke exposure enhancing self-renewal ability, increasing the expression of CSCs markers and tumorigenic ability of human bronchial epithelial cells, the IL-6/Np63/Notch axis and Wnt/-catenin pathway play an important role in this process

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Whether it is smoking cigarettes, chewing on tobacco, smoking cigars or pipes, tobacco use wreaks havoc in your mouth in more ways than one

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