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The available data suggest that p53 mutations in lung cancers can be attributed to direct DNA damage from cigarette smoke carcinogens rather than to selection of pre-existing endogenous mutations

It has notes of toasted tobacco, apple, pear, and citrus

From the first bowl I was hooked, even though those initial attempts at keeping the pipe lit left my scorched tongue feeling like a piece of dried-out shoe leather for a few weeks

I suggest starting with small doses and not trying a strenuous exercise routine. Its worth noting that cannabis can impair motor control and judgement, so it should only be used in a safe setting," Tishler adds