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Research reported in this publication was supported by grant numbers R01DA036493-02S1 and R01DA036493-04S1 from the National Institute of Drug Abuse and FDA Center for Tobacco Products (CTP)

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X i =diag( X i1 , X i2 ) is the 2 m matrix of auxiliary variables, m=m 1 +m 2 where m k is the number of explanatory variables for category k , and X ik =(x ik1 ,x ik2 , ,x ikmk ) is the set of observations corresponding to area i and category k, k=1, 2

Finding Your Perfect Nicotine Balance Uncovering your ideal nicotine balance within TEREAs product range requires careful consideration of both flavor intensity and nicotine content