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This work also has other important strengths over previous studies including the sample size, length of intervention, multiple toxicant exposure measures and control conditions. The question of whether an e-cigarettes nicotine delivery profile is predictive of its ability to reduce harm and promote behavior change among smokers remains highly relevant to policymakers, public health advocates, health care providers and smoking populations

However, public health messaging loses credibility when it relies on claims that are not supported by evidence

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However, in recent years, it has been misused in increasingly dangerous ways including being crushed and smoked