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5 Remarkably, in 2022, Klemperer et al

Inclusion criteria The inclusion criteria for studies were (i) peer-reviewed, (ii) focused on behavioral, (iii) dietary, (iv) telemedicine, (v) digital health, (vi) genomic approaches to CVD, (vii) reported clinical, public health and translational outcomes, (viii) original research articles, meta-analysis, systematic review, guideline documents and authoritative policy reports, and lastly published in English

In prospective cohort studies, snus use is associated with incident cardiovascular disease and cancer, but results are conflicting and confounding may be difficult to fully adjust for [17, 18]

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