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The authors filling in linear data points between 2010 and 2014 for their main analysis was questionable, the letter stated, and findings from an additional analysis that left out those filled-in values are hidden in the manuscript. Reading the papers supplementary materials, the letter said, revealed that most estimated associations were no longer statistically significant in that analysis

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smoking too quickly can overheat the cigar and affect the flavor, while puffing too slowly may cause it to go out

Despite these limitations, the direction of the evidence has not substantially changed in recent years, but rather has been reinforced