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DIRECT EFFECTS ON OSSEOINTEGRATION AND BONE REGENERATION Compromised Angiogenesis Nicotine, carbon monoxide, and other harmful substances in cigarettes, e-cigarettes, waterpipes, and cannabis impair angiogenesis by reducing blood flow and oxygenation

In 2010, 14.1% of Maryland high school students under 18 reported smoking cigarettes in the last 30 days, and 13.9% reported smoking cigars