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Farsalinos and colleagues (2013) conducted an online survey of more than 4,000 e-cigarette users and found that flavors, especially flavor variety, were an important factor in the maintenance of e-cigarette use by current and former smokers

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Therefore, it is important to acknowledge that population level tobacco harm reduction can only be achieved if a scientifically-substantiated reduced harm product is accepted and used by a large number of adult smokers, who would otherwise continue to smoke, while never smokers, vulnerable populations and youth do not also begin using it