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Expert Tips for Healthy Gums Diagnosis and Treatment In case of suspected oral cancer, the diagnostic workup may include: Mouth Examination by Dentist or Oncosurgeon Biopsy: Removing tissue for pathological examination (gold standard test) Image scanning through CT, MRI, or PET to stage the disease Treatment methods are influenced by staging and localization: Surgical treatment (surgery): The primary method for treating localized disease, including excision of the tumor and sometimes neck dissection