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Keep it fresh: reseal the pouch after each use to keep the natural leaf moist

We contacted RCT participants who had adolescents ages 1317, usually the adolescents mother or father, referred to hereafter as the parent. We obtained verbal consent from the parent for the adolescents participation and then verbal assent from the adolescent

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The announcement has received extensive international attention, and has been praised by the Canadian Cancer Society and other health organizations