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If you could choose, do you want to be hit by a freight train or a minivan? Spangler said, adding that when it comes to smoking just one cigarette a day, Yes, it is less risky, but its still very risky. If a patient says to me, I want to quit smoking 20 cigarettes a day, but I think I can only cut down to one [cigarette] a day, I tell them that there is some harm reduction, Spangler said

Eur J Drug Metab Pharmacokinet 42:943954 Benowitz NL, Hukkanen J, Jacob P 3rd (2009) Nicotine chemistry, metabolism, kinetics and biomarkers

The best design for a given space will depend on multiple factors, including the size of the space to be treated, the cost of materials, and the materials available