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Common flavor categories: Fruit: Strawberry, mango, watermelon Dessert: Custard, vanilla, cookie Menthol: Mint, ice, cool Tobacco: Classic and smooth blends Step 4: Mix Your Ingredients Measure each ingredient according to your recipe (use syringes for accuracy)

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Statistical analysis Cox proportional hazards models were used to examine the associations between cigar status and mortality outcomes based on underlying causes of death from the 10th revision of International Statistical Classification of Diseases and Related Health Problems (ICD-10) [21], reported as hazard ratios (HRs, with 95% confidence intervals, CI) with never smokers as the referent group