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Tobacco smoke contains over 4000 potential toxicants, including nicotine, which is an addictive alkaloid and a natural insecticide of tobacco plants, Nicotiana spp

Firstly, it reduces blood oxygen levels and constricts blood vessels, impacting the sensitive structures in the inner ear

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Circ0061052 regulation of FoxC1/Snail pathway via miR-515-5p is involved in the epithelial-mesenchymal transition of epithelial cells during cigarette smoke-induced airway remodeling