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Smoking increases metabolism of many psychotropic medications, and on smoking cessation doses of such medications require immediate dose reduction in order to prevent medication toxicity (Box 1)

By 2007, e-cigarettes were marketed in Europe and the United States by manufacturer Ruyan as a way to safely stop smoking tobacco

Among adult e-cigarette users overall, 29.4% also were current cigarette smokers, 40.3% were former cigarette smokers, and 30.3% had never been cigarette smokers

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