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Jaakkola and colleagues [25] examined the relationship between exposure to ETS and development of respiratory symptoms including dyspnea, in a population of 117 subjects who had never smoked and who were aged between 15 and 40 at the time of initial examination, and who were reexamined eight years later

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Lab studies and animal models will also be needed to track long-term effects of the presence of metals such as lead in vapes, including whether non-toxic Cr could convert into its carcinogenic form once inhaled into the lungs